Courses:

Thermodynamics of Biomolecular Systems >> Content Detail



Study Materials



Readings

Amazon logo Help support MIT OpenCourseWare by shopping at Amazon.com! MIT OpenCourseWare offers direct links to Amazon.com to purchase the books cited in this course. Click on the Amazon logo to the left of any citation and purchase the book from Amazon.com, and MIT OpenCourseWare will receive up to 10% of all purchases you make. Your support will enable MIT to continue offering open access to MIT courses.

Reading assignments are from the following textbooks:

[SAB] Amazon logo Silbey, R., R. Alberty, and M. Bawendi. Physical Chemistry. New York, NY: John Wiley & Sons, 2004. ISBN: 9780471215042.

[DB] Amazon logo Dill, Ken A., and Sarina Bromberg. Molecular Driving Forces: Statistical Thermodynamics in Chemistry and Biology. New York, NY: Routledge, 2002. ISBN: 9780815320517.


LEC #TOPICSREADINGS
1Introduction to Thermo; 0th Law; Temperature; Work; HeatSAB 1.1-1.4, 1.8-1.9, 2.1
2State Functions, 1st Law, PathsSAB 2.2-2.6
3Joule and Joule-Thompson; Heat CapacitySAB 2.7-2.9
4Reversible and Irreversible ProcessesSAB 2.10, 3.1
5ThermochemistrySAB 2.11-2.13
62nd Law; Entropy (Boltzmann and Clausius)SAB 3.2
7ΔS for Reversible and Irreversible ProcessesSAB 3.3-3.5
8Equilibrium; Maxwell Relations; Free EnergySAB 4.1-4.2, 4.9

DB 8
9Chemical Potential; Phase EquilibriumSAB 4.3-4.4, 4.6-4.7
10Chemical Equilibrium; Equilibrium ConstantSAB 5.1-5.4
11Standard States; Gibbs-DuhemSAB 4.8
12ΔG0= -RTlnK; ExampleSAB 8.1-8.2
Hour Exam 1
13Boltzmann DistributionDB 6

SAB 3.6, 16.1-16.2
14Thermo and Boltzmann DistributionDB 10 (first half)
15Occupation of StatesDB 10 (second half)
16Third LawSAB 3.8
17Phase Equilibria, Single ComponentSAB 6.1-6.2

DB 14
18Phase Equilibria II; Clausius ClapeyronSAB 6.3
19Regular Solutions; Mixing Energy; Mean FieldsDB 15

Class notes
20Nonideal Solutions
21Solvation; Colligative PropertiesDB 16

Class notes
Hour Exam 2
22Osmotic Pressure and Phase PartitioningDB 16
23Surface TensionDB 14
24Polymer 1 - Freely Jointed ChainDB 31
25Polymer 2 - Chain ConformationDB 31
26Polymer 3 - Rubber ElasticityDB 32
27Electrolyte Solutions
28Electrolytes at Interfaces; Debye LengthClass notes
29Titration of PolyelectrolytesClass notes
30Thermodynamics of DNA HybridizationClass notes
31CooperativityDB 26
Hour Exam 3
32Cooperativity, Part 2DB 28
33Cooperativity, Part 3
34Driving Forces for Self-Assembly
35Special Topic (Coarse Grain/Monte Carlo Model)
36Course Review and Evaluations

 








© 2010-2021 OpenCollege.com, All Rights Reserved.
Open College is a service mark of AmeriCareers LLC.